Cardiac stem cell therapy research in China
 
                 
                
                    
                                        
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Graphical Abstract
 
                                        
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Abstract
    For more than two decades, the morbidity and mortality of coronary artery disease (CAD) has been increasing rapidly in China. Despite tremendous advances in treatment strate-gies of CAD, heart failure after acute myocardial infarction (AMI) continues to be one of the greatest medical chal-lenges throughout the world. In 1994, Soonpaa and col-leagues first reported the possibility of cardiomyocytes implantation and suggested that intracardiac cell grafting might provide a useful approach for myocardial repair.1 Cell implantation has become a novel therapeutic option for is-chemic cardiac injury and heart failure.
 
                                        
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