How to effectively manage the refractory coronary thrombus? A systemic mini-review

Song ZHANG; Dang-Hui SUN; Shuang LI; Yue LI

doi:10.26599/1671-5411.2023.04.003

Volume 20 Issue 4

Apr. 2023

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Please cite this article as: ZHANG S, SUN DH, LI S, LI Y. How to effectively manage the refractory coronary thrombus? A systemic mini-review. J Geriatr Cardiol 2023; 20(4): 309−313. DOI: 10.26599/1671-5411.2023.04.003

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Please cite this article as: ZHANG S, SUN DH, LI S, LI Y. How to effectively manage the refractory coronary thrombus? A systemic mini-review. J Geriatr Cardiol 2023; 20(4): 309−313. DOI: 10.26599/1671-5411.2023.04.003

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How to effectively manage the refractory coronary thrombus? A systemic mini-review

doi: 10.26599/1671-5411.2023.04.003

Song ZHANG¹,
Dang-Hui SUN¹,
Shuang LI¹,
Yue LI^{1, 2, 3, 4, 5
,
,}

1.
Department of Cardiology, the First Affiliated Hospital of Harbin Medical University, Harbin, China
2.
NHC Key Laboratory of Cell Translation, Harbin Medical University, Harbin, China
3.
Key Laboratory of Hepatosplenic Surgery, Harbin Medical University, Ministry of Education, Harbin, China
4.
Key Laboratory of Cardiac Diseases and Heart Failure, Harbin Medical University, Harbin, China
5.
Heilongjiang Key Laboratory for Metabolic Disorder & Cancer Related Cardiovascular Diseases, Harbin, China

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Corresponding author: ly99ly@hrbmu.edu.cn
Available Online: 2023-04-18
Publish Date: 2023-04-28

Abstract

Abstract

The main management principle for patients with coronary thrombus should be “more removal and less implantation”. Routine thrombus aspiration (TA) is ineffective for intracoronary thrombus or high residual thrombus burden after TA and may result in a refractory coronary thrombus. It is unwise to implant a stent in the vessel with high residual thrombus, which is associated with no-reflow, impaired microvascular perfusion, and consequently worse clinical outcomes. Therefore, increasing the efficiency of TA during percutaneous coronary intervention procedures, especially under some conditions of refractory coronary thrombus, is very important to restore myocardial reperfusion and improve microvascular dysfunction early. In the present work, we aimed to demonstrate the factors that may affect TA efficiency and introduce several highly effective approaches to treat refractory coronary thrombus.

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References(19)

References

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