ISSN 1671-5411 CN 11-5329/R
Nooraldaem Yousif, Slayman Obeid, Ronald Binder, Andrea Denegri, Mohammady Shahin, Christian Templin, Thomas F Lüscher. Impact of gender on outcomes after transcatheter aortic valve implantation. J Geriatr Cardiol 2018; 15(6): 394-400. doi: 10.11909/j.issn.1671-5411.2018.06.013
Citation: Nooraldaem Yousif, Slayman Obeid, Ronald Binder, Andrea Denegri, Mohammady Shahin, Christian Templin, Thomas F Lüscher. Impact of gender on outcomes after transcatheter aortic valve implantation. J Geriatr Cardiol 2018; 15(6): 394-400. doi: 10.11909/j.issn.1671-5411.2018.06.013

Impact of gender on outcomes after transcatheter aortic valve implantation

doi: 10.11909/j.issn.1671-5411.2018.06.013
Funds:

Lüscher TF has received research and educartional grants from Medtronic, Inc., Tollachenaz and Switzerland, Edwards Inc., to the institution. Obeid S and Denegri A were supported by grants of the Zurich Heart House— Foundation

  • Received Date: 2017-12-24
  • Rev Recd Date: 2018-02-11
  • Publish Date: 2018-06-28
  • Background The influence of gender on clinical outcomes following transcatheter aortic valve implantation (TAVI) was considerably discrepant in previous studies. We aimed to investigate the impact of gender in our registry. Methods The study is a retrospective observational analysis of a prospectively designed cohort (546 consecutive patients treated at the University Hospital Zurich who were enrolled in Swiss TAVI Cohort from May 2008 to April 2014). The Study took place in University Heart Centre at University Hospital Zurich, Switzerland. Results Both genders were equally represented with 51.5 % (n= 281) of the populations being females, who were significantly older and had a more pronounced history of hypertension (P P = 0.004), coronary artery disease (P P P= 0.018). Patients were followed up for a median of 391 days with a 100% complete follow-up at one year. The primary outcome (all-cause mortality) occurred in 6.8% (n = 37) and 15% (n = 82) of patients at 30 days and one year, respectively. The 30-day all-cause mortality outcome did not significantly differ between females (7.5%) and males (6.0%) (P = 0.619), but one year all-cause mortality occurred significantly more in males than in females (18.7% vs. 11.7%,P Conclusions After TAVI implantation for severe aortic stenosis, males have a less favorable long-term (one year) mortality outcome than females.
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