ISSN 1671-5411 CN 11-5329/R
Eiji Ichimoto, Adam Arnofsky, Michael Wilderman, Richard Goldweit, Joseph De Gregorio. Early mortality and safety after transcatheter aortic valve replacement using the SAPIEN 3 in nonagenarians. J Geriatr Cardiol 2018; 15(6): 387-393. doi: 10.11909/j.issn.1671-5411.2018.06.002
Citation: Eiji Ichimoto, Adam Arnofsky, Michael Wilderman, Richard Goldweit, Joseph De Gregorio. Early mortality and safety after transcatheter aortic valve replacement using the SAPIEN 3 in nonagenarians. J Geriatr Cardiol 2018; 15(6): 387-393. doi: 10.11909/j.issn.1671-5411.2018.06.002

Early mortality and safety after transcatheter aortic valve replacement using the SAPIEN 3 in nonagenarians

doi: 10.11909/j.issn.1671-5411.2018.06.002
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  • Received Date: 2018-02-01
  • Rev Recd Date: 2018-02-01
  • Publish Date: 2018-06-28
  • Background Transcatheter aortic valve replacement (TAVR) has been performed for many elderly patients with severe aortic stenosis (AS). The SAPIEN 3 is one of the latest balloon-expandable prosthesis. This study aimed to investigate the early clinical outcomes after TAVR using the SAPIEN 3 in nonagenarians. Methods A total of 97 consecutive patients underwent TAVR for severe AS between December 2015 and December 2016. Of these, 85 consecutive patients who underwent TAVR using the SAPIEN 3 were included. According to the age, patients were classified into age ≥ 90 years group (17 patients) or age Results The Society of Thoracic Surgeons score in age ≥ 90 years group was higher than age vs. 8.5 ± 5.1%, P vs. 1.5%, P = 0.04 and 11.8% vs. 1.5%, P= 0.04, respectively). The composite endpoint of early safety at 30 days was similar between the two groups. Multivariate logistic regression analysis showed that prior myocardial infarction was an independent predictor of the composite endpoint of early safety (odds ratio: 4.76, 95% confidence interval: 1.02–22.21, P = 0.047). Conclusions The early mortality and safety after TAVR using the SAPIEN 3 in nonagenarians were similar and acceptable despite of higher operative risk.
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