Telat Keles, Huseyin Ayhan, Tahir Durmaz, Cenk Sari, Abdullah Nabi Aslan, Kemal Esref Erdogan, Haci Ahmet Kasapkara, Emine Bilen, Nihal Akar Bayram, Murat Akcay, Engin Bozkurt. Improvement in renal functions with transcatheter aortic valve implantation[J]. Journal of Geriatric Cardiology, 2013, 10(4): 317-322. DOI: 10.3969/j.issn.1671-5411.2013.04.010
Citation: Telat Keles, Huseyin Ayhan, Tahir Durmaz, Cenk Sari, Abdullah Nabi Aslan, Kemal Esref Erdogan, Haci Ahmet Kasapkara, Emine Bilen, Nihal Akar Bayram, Murat Akcay, Engin Bozkurt. Improvement in renal functions with transcatheter aortic valve implantation[J]. Journal of Geriatric Cardiology, 2013, 10(4): 317-322. DOI: 10.3969/j.issn.1671-5411.2013.04.010

Improvement in renal functions with transcatheter aortic valve implantation

  • Background & Objectives In recent years, emerging transcatheter aortic valve implantation (TAVI) has become an alternative for surgery. However, with advanced age, several co-morbid factors together with contrast agent usage can cause deterioration in renal function and increase in the risk of acute kidney injury (AKI) with poor prognosis in patients with AKI. Therefore, many patients cannot benefit from this treatment. In this study, we aim to examine the effects of TAVI on renal functions. Methods and Results Seventy patients, mean age of 77.6 years, underwent TAVI between July 2011 and December 2012. Estimated glomerular filtration rate (eGFR) was calculated by using the Cockcroft and Gault Formula. Patients were monitored for 48 h for urine output. Stage 1 AKI, according to the VARC-2 AKIN system, developed in only five (7.1%) of the patients after the procedure. There was a statistically significant increase between the mean 1st month eGFRs before (68.2 vs. 61.0, P vs. 63.6, P P st month (52.1 mL/min, P P P Conclusions In this study, we showed that the treatment of aortic stenosis through TAVI allows improvement of renal functions, and that AKI rates will be lower with careful patient selection, proper pre-procedural hydration, and careful use of contrast agent.
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