Mustafa Adem Tatlisu, Kazim Serhan Ozcan, Baris Gungor, Ahmet Zengin, Mehmet Baran Karatas, Zekeriya Nurkalem. Inappropriate use of digoxin in patients presenting with digoxin toxicity[J]. Journal of Geriatric Cardiology, 2015, 12(2): 143-146. DOI: 10.11909/j.issn.1671-5411.2015.02.007
Citation: Mustafa Adem Tatlisu, Kazim Serhan Ozcan, Baris Gungor, Ahmet Zengin, Mehmet Baran Karatas, Zekeriya Nurkalem. Inappropriate use of digoxin in patients presenting with digoxin toxicity[J]. Journal of Geriatric Cardiology, 2015, 12(2): 143-146. DOI: 10.11909/j.issn.1671-5411.2015.02.007

Inappropriate use of digoxin in patients presenting with digoxin toxicity

  • Background Digoxin remains widely used today despite its narrow therapeutic index and toxicity. The objective of this study was to investigate the percentage of inappropriate use of digoxin and long-term outcomes of elderly patients hospitalized for digoxin toxicity. Methods The study included 99 consecutive patients hospitalized for digoxin toxicity. The other study criteria for the inappropriate use of digoxin was regarded if participants having depressed left ventricular systolic function (ejection fraction Results Appropriate digoxin usage was confirmed in 33 of patients in spite of its narrow thera-peutic index. A total of 16 of 99 patients died, with a mean follow-up time of 22.1 ± 10.3 months. Conclusions Contrary to popular belief, the rate of inappropriate digoxin usage remains high. On account of its narrow therapeutic index and toxicity, digoxin should be used more carefully according to the current evidence and guidelines.
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