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Research Article
 
DOI:10.11909/j.issn.1671-5411.2018.06.007
Predictive value of red cell distribution width on left atrial thrombus or left atrial spontaneous echo contrast in patients with non-valvular atrial fibrillation
Xian-Zhang ZHAN,Wei-Dong LIN,Fang-Zhou LIU,Yu-Mei XUE,Hong-Tao LIAO,Xin LI,Xian-Hong FANG,Hai DENG,Jun HUANG,Yang-Qiu LI,Jo-Jo HAI,Hung-Fat Tse,Shu-Lin WU.Predictive Value of Red Cell Distribution Width on Left Atrial Thrombus or Left Atrial Spontaneous Echo Contrast in Patients with Non-valvar Atrial FibrillationJ Geriatr Cardiol 2018,15(6):408~412
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Authors:Xian-Zhang ZHAN1;Wei-Dong LIN2;Fang-Zhou LIU2;Yu-Mei XUE2;Hong-Tao LIAO2;Xin LI2;Xian-Hong FANG2;Hai DENG2;Jun HUANG2;Yang-Qiu LI3;Jo-Jo HAI4;Hung-Fat Tse5;Shu-Lin WU6

Author Affiliation:1.Department of Hematology, the First Affiliated Hospital, Jinan University, Guangzhou, China;Department of Cardiology, Atrial Fibrillation Center, Guangdong CardiovascularInstitute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China;2.Department of Cardiology, Atrial Fibrillation Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China;3.Department of Hematology, the First Affiliated Hospital, Jinan University, Guangzhou, China;4.Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, China;Division of Cardiology, Department of Medicine, the University of Hong Kong Shenzhen Hospital, Shenzhen, China;5.Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, China;Division of Cardiology, Department of Medicine, the University of Hong Kong Shenzhen Hospital, Shenzhen,China;6.Department of Hematology, the First Affiliated Hospital, Jinan University, Guangzhou, China

Foundation:

Abstract: Objective To evaluate the predictive value of red cell distribution width (RDW) on left atrial thrombus (LAT) or left atrial spontaneous echo contrast (LASEC) in patients with non-valvular atrial fibrillation (AF). Methods We reviewed 692 patients who were diagnosed as non-valvular AF and underwent transesophageal echocardiography (TEE) in Guangdong Cardiovascular Institute from April 2014 to December 2015. The baseline clinical characteristics, laboratory test of blood routine, electrocardiograph measurements were analyzed. Results Eighty-four patients were examined with LAT/LASEC under TEE. The mean RDW level was significantly higher in LAT/LASEC patients compared with the non-LAT/LASEC patients (13.59% ± 1.07% vs. 14.34% ± 1.34%; P < 0.001). Receiver–operating characteristic curve analysis was performed and indicated the best RDW cut point was 13.16%. Furthermore, multivariate logistic regression analysis indicated that RDW level > 13.16% could be an independent risk factor for LAT/LASEC in patients with AF. Conclusion Elevated RDW level is associated with the presence of LAT/LASEC and could be with moderate predictive value for LAT/LASEC in patients with non-valvular AF.

Keywords:

Atrial fibrillation; Left atrial spontaneous echo contrast; Left atrial thrombus; Red cell distribution width
Received:November 25, 2017        Accepted:March 20, 2018   Published Online:June 28, 2018
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