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Research Article
 
DOI:10.3724/SP.J.1263.2011.00093
Coronary collateral circulation: Effects on outcomes of acute anterior myocardial infarction after primary percutaneous coronary intervention
Bin Wang,Ya-Ling Han,Yi Li,Quan-Min Jing,Shou-Li Wang,Ying-Yan Ma,Geng Wang,Bo Luan,Xiao-Zeng Wang.J Geriatr Cardiol 2011,8(2):93~98
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Authors:Bin Wang1;Ya-Ling Han1;Yi Li1;Quan-Min Jing1;Shou-Li Wang1;Ying-Yan Ma1;Geng Wang1;Bo Luan1;Xiao-Zeng Wang1

Author Affiliation:1.Department of Cardiology, Shenyang North Hospital, Shenyang 110016, Liao Ning Province, China;

Foundation:

Abstract: Background To investigate the effects of collateral coronary circulation on the outcome of the patients with anterior myocardial infarction (MI) with left anterior desending artery occlusion abruptly. Methods Data of 189 patients with acute anterior MI who had a primary percutaneous coronary intervention (PCI) in the first 12 h from the onset of symptoms between January 2004 and December 2008 were retrospective analyzed. Left anterior descending arteries (LAD) of all patients were occluded. LADs were reopened with primary PCI. According to the collateral circulation, all patients were classified to two groups: no collateral group (n = 111), patients without angiographic collateral filling of LAD or side branches (collateral index 0) and collateral group (n = 78), and patients with angiographic collateral filling of LAD or side branches (collateral index 1, 2 or 3). At one year’s follow-up, the occurrence of death, reinfarction, stent thrombosis (ST), target vessel revascularization and readmission because of heart failure were observed. Results At one year, the mortality was lower in patients with collateral circulation compared with those without collateral circulation (1% vs. 8%, P = 0.049), whereas there were no differences in the occurrence of reinfarction, ST, target vessel revascularization and readmission because of heart failure. The occurrence of composite of endpoint was lower in patients with collateral circulation compared with those without collateral circulation (12% vs. 26%; P = 0.014). Conclusions Pre-exist collateral circulation may prefigure the satisfactory prognosis to the patients with acute anterior MI after primary PCI in the first 12 h of MI onset.

Keywords:

collateral circulation; myocardial infarction; mortality; left anterior descending artery
Received:February 13, 2011        Accepted:March 06, 2011   Published Online:June 28, 2011
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